Comparative Study of Estimation of Fexofenadine Hydrochloride By Uv-Visible Spectrophotometry and Hplc Method G.R.Barabde
نویسنده
چکیده
Simple and accurate spectrophotometric and HPLC method was developed for determination of Fexofenadine in tablets dosage form. The spectrophotometric method was developed by dissolving tablets in 1:1 Methanol to make solution of 10ppm giving absorbance at 220nm. The experimental conditions were optimized and Beers law was obeyed over the applicable concentration range. The application of HPLC procedure depends on using a conventional reverse phase C18 column along with mobile phase consisting of 1:1 Methanol. Both techniques were applied successfully for analysis of Fexofenadine in three different commercially available tablets. From the results obtained for both procedures percentage purity was found out.
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